NASA has only planned (and budgeted) for this single test flight before putting humans on the next flight of SLS, currently expected in 2024. That means the space agency will have to learn everything it can from this one flight and fix any kinks or concerns that arise on the ground before putting astronauts in Orion for Artemis II.
For Artemis I, Orion will be sent on a trajectory around the far side of the moon that will carry the vehicle farther beyond our natural satellite than than any Apollo astronauts traveled, or any other spacecraft designed for humans, for that matter. At its maximum distance from Earth it will be about 280,000 miles (450,600 kilometers) from home.
There are no humans on this flight, but there is one ungulate and one member of many families. A plush Shaun the Sheep toy will have a swell view of the moon and Earth from Orion as part of a promotional partnership.
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